Human AGXT2 activation kit by CRISPRa

CAT#: GA112192

AGXT2 CRISPRa kit - CRISPR gene activation of human alanine--glyoxylate aminotransferase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AGXT2
• Locus ID: 64902
• Kit Components:

  GA112192G1, AGXT2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112192G2, AGXT2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112192G3, AGXT2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001306173, NM_031900
• Synonyms: AGT2; DAIBAT
• Summary: The protein encoded by this gene is a class III pyridoxal-phosphate-dependent mitochondrial aminotransferase. It catalyzes the conversion of glyoxylate to glycine using L-alanine as the amino donor. It is an important regulator of methylarginines and is involved in the control of blood pressure in kidney. Polymorphisms in this gene affect methylarginine and beta-aminoisobutyrate metabolism, and are associated with carotid atherosclerosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]