Human SLC30A5 activation kit by CRISPRa

CAT#: GA112196

SLC30A5 CRISPRa kit - CRISPR gene activation of human solute carrier family 30 member 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLC30A5
• Locus ID: 64924
• Kit Components:

  GA112196G1, SLC30A5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112196G2, SLC30A5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112196G3, SLC30A5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001251969, NM_022902, NM_024055
• Synonyms: ZnT-5; ZNT5; ZNTL1; ZTL1
• Summary: This gene encodes a member of the SLC30A/ZnT family of zinc transporter proteins. ZnT proteins mediate both cellular zinc efflux and zinc sequestration into membrane-bound organelles. The encoded protein plays a role in the early secretory pathway as a heterodimer with zinc transporter 6, and may also regulate zinc sequestration into secretory granules of pancreatic beta cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 19. [provided by RefSeq, Oct 2011]