Human PINK1 activation kit by CRISPRa

CAT#: GA112222

PINK1 CRISPRa kit - CRISPR gene activation of human PTEN induced kinase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PINK1
• Locus ID: 65018
• Kit Components:

  GA112222G1, PINK1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112222G2, PINK1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112222G3, PINK1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_032409
• Synonyms: BRPK; PARK6
• Summary: This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease. [provided by RefSeq, Jul 2008]