Human CUEDC2 activation kit by CRISPRa

CAT#: GA112304

CUEDC2 CRISPRa kit - CRISPR gene activation of human CUE domain containing 2


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol CUEDC2
Locus ID 79004
Kit Components

GA112304G1, CUEDC2 gRNA vector 1 in pCas-Guide-CRISPRa

GA112304G2, CUEDC2 gRNA vector 2 in pCas-Guide-CRISPRa

GA112304G3, CUEDC2 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_024040
Synonyms bA18I14.5; C10orf66
Summary Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism. [UniProtKB/Swiss-Prot Function]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.