Human CUEDC2 activation kit by CRISPRa
CAT#: GA112304
CUEDC2 CRISPRa kit - CRISPR gene activation of human CUE domain containing 2
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | CUEDC2 |
Locus ID | 79004 |
Kit Components | GA112304G1, CUEDC2 gRNA vector 1 in pCas-Guide-CRISPRa GA112304G2, CUEDC2 gRNA vector 2 in pCas-Guide-CRISPRa GA112304G3, CUEDC2 gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_024040 |
Synonyms | bA18I14.5; C10orf66 |
Summary | Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism. [UniProtKB/Swiss-Prot Function] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN400790 | CUEDC2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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