Human ALG8 activation kit by CRISPRa

CAT#: GA112336

ALG8 CRISPRa kit - CRISPR gene activation of human ALG8 alpha-1,3-glucosyltransferase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ALG8
• Locus ID: 79053
• Kit Components:

  GA112336G1, ALG8 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112336G2, ALG8 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112336G3, ALG8 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001007027, NM_001007028, NM_024079
• Synonyms: CDG1H
• Summary: This gene encodes a member of the ALG6/ALG8 glucosyltransferase family. The encoded protein catalyzes the addition of the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation of proteins. Mutations in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ih). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]