Human ALG12 activation kit by CRISPRa

CAT#: GA112359

ALG12 CRISPRa kit - CRISPR gene activation of human ALG12 alpha-1,6-mannosyltransferase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ALG12
• Locus ID: 79087
• Kit Components:

  GA112359G1, ALG12 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112359G2, ALG12 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112359G3, ALG12 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_024105
• Synonyms: CDG1G; ECM39; hALG12; PP14673
• Summary: This gene encodes a member of the glycosyltransferase 22 family. The encoded protein catalyzes the addition of the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation. Mutations in this gene have been associated with congenital disorder of glycosylation type Ig (CDG-Ig)characterized by abnormal N-glycosylation. [provided by RefSeq, Jul 2008]