Human LENG4 (MBOAT7) activation kit by CRISPRa

CAT#: GA112381

MBOAT7 CRISPRa kit - CRISPR gene activation of human membrane bound O-acyltransferase domain containing 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MBOAT7
• Locus ID: 79143
• Kit Components:

  GA112381G1, MBOAT7 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112381G2, MBOAT7 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112381G3, MBOAT7 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001146056, NM_001146082, NM_001146083, NM_024298
• Synonyms: BB1; hMBOA-7; LENG4; LPIAT; LRC4; MBOA7; OACT7
• Summary: This gene encodes a member of the membrane-bound O-acyltransferases family of integral membrane proteins that have acyltransferase activity. The encoded protein is a lysophosphatidylinositol acyltransferase that has specificity for arachidonoyl-CoA as an acyl donor. This protein is involved in the reacylation of phospholipids as part of the phospholipid remodeling pathway known as the Land cycle. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]