Human CPSF7 activation kit by CRISPRa

CAT#: GA112691

CPSF7 CRISPRa kit - CRISPR gene activation of human cleavage and polyadenylation specific factor 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CPSF7
• Locus ID: 79869
• Kit Components:

  GA112691G1, CPSF7 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112691G2, CPSF7 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112691G3, CPSF7 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001136040, NM_001142565, NM_024811
• Synonyms: CFIm59
• Summary: Cleavage factor Im (CFIm) is one of six factors necessary for correct cleavage and polyadenylation of pre-mRNAs. CFIm is composed of three different subunits of 25, 59, and 68 kDa, and it functions as a heterotetramer, with a dimer of the 25 kDa subunit binding to two of the 59 or 68 kDa subunits. The protein encoded by this gene represents the 59 kDa subunit, which can interact with the splicing factor U2 snRNP Auxiliary Factor (U2AF) 65 to link the splicing and polyadenylation complexes. [provided by RefSeq, Oct 2016]