Human Dehydrodolichyl Diphosphate Synthase (DHDDS) activation kit by CRISPRa

CAT#: GA112748

DHDDS CRISPRa kit - CRISPR gene activation of human dehydrodolichyl diphosphate synthase subunit

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DHDDS
• Locus ID: 79947
• Kit Components:

  GA112748G1, DHDDS gRNA vector 1 in pCas-Guide-CRISPRa

  GA112748G2, DHDDS gRNA vector 2 in pCas-Guide-CRISPRa

  GA112748G3, DHDDS gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001243564, NM_001243565, NM_001319959, NM_024887, NM_205861
• Synonyms: CIT; CPT; DS; HDS; RP59
• Summary: The protein encoded by this gene catalyzes cis-prenyl chain elongation to produce the polyprenyl backbone of dolichol, a glycosyl carrier lipid required for the biosynthesis of several classes of glycoproteins. Mutations in this gene are associated with retinitis pigmentosa type 59. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]