Human PGAP1 activation kit by CRISPRa

CAT#: GA112807

PGAP1 CRISPRa kit - CRISPR gene activation of human post-GPI attachment to proteins 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PGAP1
• Locus ID: 80055
• Kit Components:

  GA112807G1, PGAP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112807G2, PGAP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112807G3, PGAP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001321099, NM_001321100, NM_024989
• Synonyms: Bst1; ISPD3024; MRT42; SPG67
• Summary: The protein encoded by this gene functions early in the glycosylphosphatidylinositol (GPI) biosynthetic pathway, catalyzing the inositol deacylation of GPI. The encoded protein is required for the production of GPI that can attach to proteins, and this may be an important factor in the transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi. Defects in this gene are a cause an autosomal recessive form of cognitive impairment. [provided by RefSeq, Jul 2017]