Human C8ORF41 (TTI2) activation kit by CRISPRa

CAT#: GA112857

TTI2 CRISPRa kit - CRISPR gene activation of human TELO2 interacting protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TTI2
• Locus ID: 80185
• Kit Components:

  GA112857G1, TTI2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112857G2, TTI2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112857G3, TTI2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001102401, NM_001265581, NM_001330505, NM_025115
• Synonyms: C8orf41; MRT39
• Summary: This gene encodes a regulator of the DNA damage response. The protein is a component of the Triple T complex (TTT) which also includes telomere length regulation protein and TELO2 interacting protein 1. The TTT complex is involved in cellular resistance to DNA damage stresses and may act as a regulator of phosphoinositide-3-kinase-related protein kinase (PIKK) abundance. [provided by RefSeq, May 2013]