Human INO80B activation kit by CRISPRa

CAT#: GA113168

INO80B CRISPRa kit - CRISPR gene activation of human INO80 complex subunit B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: INO80B
• Locus ID: 83444
• Kit Components:

  GA113168G1, INO80B gRNA vector 1 in pCas-Guide-CRISPRa

  GA113168G2, INO80B gRNA vector 2 in pCas-Guide-CRISPRa

  GA113168G3, INO80B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_031288
• Synonyms: hIes2; HMGA1L4; HMGIYL4; IES2; PAP-1BP; PAPA-1; PAPA1; ZNHIT4
• Summary: This gene encodes a subunit of an ATP-dependent chromatin remodeling complex, INO80, which plays a role in DNA and nucleosome-activated ATPase activity and ATP-dependent nucleosome sliding. Readthrough transcription of this gene into the neighboring downstream gene, which encodes WW domain-binding protein 1, generates a non-coding transcript. [provided by RefSeq, Feb 2011]