Human Aph 1b (APH1B) activation kit by CRISPRa

CAT#: GA113180

APH1B CRISPRa kit - CRISPR gene activation of human aph-1 homolog B, gamma-secretase subunit

SDS

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Find the corresponding CRISPRi Inhibitor Kit

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol APH1B
Locus ID 83464
Kit Components

GA113180G1, APH1B gRNA vector 1 in pCas-Guide-CRISPRa

GA113180G2, APH1B gRNA vector 2 in pCas-Guide-CRISPRa

GA113180G3, APH1B gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058
Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001145646, NM_031301
Synonyms APH-1B; PRO1328; PSFL; TAAV688
Summary This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein. [provided by RefSeq, Sep 2011]

Other Versions

SKU Description Size Price
KN405070 APH1B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
    • 1 kit

USD 1,290.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.