Human RILP activation kit by CRISPRa

CAT#: GA113197

RILP CRISPRa kit - CRISPR gene activation of human Rab interacting lysosomal protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RILP
• Locus ID: 83547
• Kit Components:

  GA113197G1, RILP gRNA vector 1 in pCas-Guide-CRISPRa

  GA113197G2, RILP gRNA vector 2 in pCas-Guide-CRISPRa

  GA113197G3, RILP gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_031430
• Synonyms: PP10141
• Summary: This gene encodes a lysosomal protein that interacts with RAB7, a small GTPase that controls transport to endocytic degradative compartments. Studies using mutant forms of the two proteins suggest that this protein represents a downstream effector for RAB7, and both proteins act together in the regulation of late endocytic traffic. A unique region of this protein has also been shown to be involved in the regulation of lysosomal morphology. [provided by RefSeq, Sep 2011]