Human TM2D2 activation kit by CRISPRa

CAT#: GA113289

TM2D2 CRISPRa kit - CRISPR gene activation of human TM2 domain containing 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TM2D2
• Locus ID: 83877
• Kit Components:

  GA113289G1, TM2D2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113289G2, TM2D2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113289G3, TM2D2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001024380, NM_001024381, NM_031940, NM_078473
• Synonyms: BLP1
• Summary: The protein encoded by this gene contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily. This protein has sequence and structural similarities to the beta-amyloid binding protein (BBP), but, unlike BBP, it does not regulate a response to beta-amyloid peptide. This protein may have regulatory roles in cell death or proliferation signal cascades. This gene has multiple alternatively spliced transcript variants which encode two different isoforms. [provided by RefSeq, Jul 2008]