Human B3GNT5 activation kit by CRISPRa

CAT#: GA113337

B3GNT5 CRISPRa kit - CRISPR gene activation of human UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: B3GNT5
• Locus ID: 84002
• Kit Components:

  GA113337G1, B3GNT5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113337G2, B3GNT5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113337G3, B3GNT5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_032047
• Synonyms: B3GN-T5; beta3Gn-T5
• Summary: This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II membrane protein. It exhibits strong activity to transfer GlcNAc to glycolipid substrates and is identified as the most likely candidate for lactotriaosylceramide synthase. This enzyme is essential for the expression of Lewis X epitopes on glycolipids. [provided by RefSeq, Jul 2008]