Human POLR1B activation kit by CRISPRa
CAT#: GA113406
POLR1B CRISPRa kit - CRISPR gene activation of human RNA polymerase I subunit B
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | POLR1B |
Locus ID | 84172 |
Kit Components | GA113406G1, POLR1B gRNA vector 1 in pCas-Guide-CRISPRa GA113406G2, POLR1B gRNA vector 2 in pCas-Guide-CRISPRa GA113406G3, POLR1B gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001137604, NM_001282772, NM_001282774, NM_001282776, NM_001282777, NM_001282779, NM_019014, NM_032212 |
Synonyms | RPA2; RPA135; Rpo1-2 |
Summary | Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depending on the species. Most of the mass of the pol I complex derives from the 2 largest subunits, Rpa1 and Rpa2 in yeast. POLR1B is homologous to Rpa2 (Seither and Grummt, 1996 [PubMed 8921381]). [supplied by OMIM, Mar 2008] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN420367 | POLR1B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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