Human FBXW9 activation kit by CRISPRa

CAT#: GA113458

FBXW9 CRISPRa kit - CRISPR gene activation of human F-box and WD repeat domain containing 9

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FBXW9
• Locus ID: 84261
• Kit Components:

  GA113458G1, FBXW9 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113458G2, FBXW9 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113458G3, FBXW9 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_032301
• Synonyms: Fbw9
• Summary: Members of the F-box protein family, such as FBXW9, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]). [supplied by OMIM, Mar 2008]