Human ING5 activation kit by CRISPRa

CAT#: GA113486

ING5 CRISPRa kit - CRISPR gene activation of human inhibitor of growth family member 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ING5
• Locus ID: 84289
• Kit Components:

  GA113486G1, ING5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113486G2, ING5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113486G3, ING5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001330161, NM_001330162, NM_032329
• Synonyms: p28ING5
• Summary: This gene encodes a tumor suppressor protein that inhibits cell growth and induces apoptosis. This protein contains a PHD-type zinc finger. It interacts with tumor suppressor p53 and p300, a component of the histone acetyl transferase complex, suggesting a role in transcriptional regulation. Alternative splicing and the use of multiple promoters and 3' terminal exons results in multiple transcript variants. [provided by RefSeq, Aug 2016]