Human SLD5 (GINS4) activation kit by CRISPRa

CAT#: GA113492

GINS4 CRISPRa kit - CRISPR gene activation of human GINS complex subunit 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GINS4
• Locus ID: 84296
• Kit Components:

  GA113492G1, GINS4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113492G2, GINS4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113492G3, GINS4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_032336
• Synonyms: SLD5
• Summary: The yeast heterotetrameric GINS complex is made up of Sld5, Psf1 (GINS1; MIM 610608), Psf2 (GINS2; MIM 610609), and Psf3 (GINS3; MIM 610610). The formation of the GINS complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex. [supplied by OMIM, Mar 2008]