Human COA8 activation kit by CRISPRa

CAT#: GA113526

COA8 CRISPRa kit - CRISPR gene activation of human cytochrome c oxidase assembly factor 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: COA8
• Locus ID: 84334
• Kit Components:

  GA113526G1, COA8 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113526G2, COA8 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113526G3, COA8 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001302652, NM_001302653, NM_001302654, NM_032374, NR_126431, NR_126432, NM_001370595
• Synonyms: APOP; APOP1; C14orf153
• Summary: This gene encodes a protein that localizes to the mitochondria, where it stimulates the release of cytochrome c, thereby promoting programmed cell death. Mutations in this gene have been found in individuals with mitochondrial complex IV deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]