Human COG8 activation kit by CRISPRa

CAT#: GA113531

COG8 CRISPRa kit - CRISPR gene activation of human component of oligomeric golgi complex 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: COG8
• Locus ID: 84342
• Kit Components:

  GA113531G1, COG8 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113531G2, COG8 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113531G3, COG8 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_032382
• Synonyms: CDG2H; DOR1
• Summary: This gene encodes a protein that is a component of the conserved oligomeric Golgi (COG) complex, a multiprotein complex that plays a structural role in the Golgi apparatus, and is involved in intracellular membrane trafficking and glycoprotein modification. Mutations in this gene cause congenital disorder of glycosylation, type IIh, a disease that is characterized by under-glycosylated serum proteins, and whose symptoms include severe psychomotor retardation, failure to thrive, seizures, and dairy and wheat product intolerance. [provided by RefSeq, Jul 2008]