Human DOT1L activation kit by CRISPRa
CAT#: GA113549
DOT1L CRISPRa kit - CRISPR gene activation of human DOT1 like histone lysine methyltransferase
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | DOT1L |
Locus ID | 84444 |
Kit Components | GA113549G1, DOT1L gRNA vector 1 in pCas-Guide-CRISPRa GA113549G2, DOT1L gRNA vector 2 in pCas-Guide-CRISPRa GA113549G3, DOT1L gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_032482 |
Synonyms | DOT1; KMT4 |
Summary | The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes. [provided by RefSeq, Aug 2011] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN418547 | DOT1L - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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