Human DOT1L activation kit by CRISPRa

CAT#: GA113549

DOT1L CRISPRa kit - CRISPR gene activation of human DOT1 like histone lysine methyltransferase


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol DOT1L
Locus ID 84444
Kit Components

GA113549G1, DOT1L gRNA vector 1 in pCas-Guide-CRISPRa

GA113549G2, DOT1L gRNA vector 2 in pCas-Guide-CRISPRa

GA113549G3, DOT1L gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_032482
Synonyms DOT1; KMT4
Summary The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes. [provided by RefSeq, Aug 2011]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.