Human ACRBP activation kit by CRISPRa

CAT#: GA113578

ACRBP CRISPRa kit - CRISPR gene activation of human acrosin binding protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ACRBP
• Locus ID: 84519
• Kit Components:

  GA113578G1, ACRBP gRNA vector 1 in pCas-Guide-CRISPRa

  GA113578G2, ACRBP gRNA vector 2 in pCas-Guide-CRISPRa

  GA113578G3, ACRBP gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_032489
• Synonyms: CT23; OY-TES-1; SP32
• Summary: The protein encoded by this gene is similar to proacrosin binding protein sp32 precursor found in mouse, guinea pig, and pig. This protein is located in the sperm acrosome and is thought to function as a binding protein to proacrosin for packaging and condensation of the acrosin zymogen in the acrosomal matrix. This protein is a member of the cancer/testis family of antigens and it is found to be immunogenic. In normal tissues, this mRNA is expressed only in testis, whereas it is detected in a range of different tumor types such as bladder, breast, lung, liver, and colon. [provided by RefSeq, Jul 2008]