Human MCEE activation kit by CRISPRa

CAT#: GA113659

MCEE CRISPRa kit - CRISPR gene activation of human methylmalonyl-CoA epimerase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MCEE
• Locus ID: 84693
• Kit Components:

  GA113659G1, MCEE gRNA vector 1 in pCas-Guide-CRISPRa

  GA113659G2, MCEE gRNA vector 2 in pCas-Guide-CRISPRa

  GA113659G3, MCEE gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_032601
• Synonyms: GLOD2
• Summary: The product of this gene catalyzes the interconversion of D- and L-methylmalonyl-CoA during the degradation of branched chain amino acids. odd chain-length fatty acids, and other metabolites. Mutations in this gene result in methylmalonyl-CoA epimerase deficiency, which is presented as mild to moderate methylmalonic aciduria. [provided by RefSeq, Jul 2008]