Human Sts1 (UBASH3B) activation kit by CRISPRa

CAT#: GA113801

UBASH3B CRISPRa kit - CRISPR gene activation of human ubiquitin associated and SH3 domain containing B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: UBASH3B
• Locus ID: 84959
• Kit Components:

  GA113801G1, UBASH3B gRNA vector 1 in pCas-Guide-CRISPRa

  GA113801G2, UBASH3B gRNA vector 2 in pCas-Guide-CRISPRa

  GA113801G3, UBASH3B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_032873, NM_001363365
• Synonyms: p70; STS-1; STS1; TULA-2; TULA2
• Summary: This gene encodes a protein that contains a ubiquitin associated domain at the N-terminus, an SH3 domain, and a C-terminal domain with similarities to the catalytic motif of phosphoglycerate mutase. The encoded protein was found to inhibit endocytosis of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor. [provided by RefSeq, Jul 2008]