Human ALG2 activation kit by CRISPRa

CAT#: GA113861

ALG2 CRISPRa kit - CRISPR gene activation of human ALG2 alpha-1,3/1,6-mannosyltransferase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ALG2
• Locus ID: 85365
• Kit Components:

  GA113861G1, ALG2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113861G2, ALG2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113861G3, ALG2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_033087, NM_197973, NR_024532
• Synonyms: CDGIi; hALPG2; NET38
• Summary: This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]