Human SIGLEC10 activation kit by CRISPRa

CAT#: GA113929

SIGLEC10 CRISPRa kit - CRISPR gene activation of human sialic acid binding Ig like lectin 10

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SIGLEC10
• Locus ID: 89790
• Kit Components:

  GA113929G1, SIGLEC10 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113929G2, SIGLEC10 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113929G3, SIGLEC10 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001171156, NM_001171157, NM_001171158, NM_001171159, NM_001171160, NM_001171161, NM_033130, NM_001322105
• Synonyms: PRO940; SIGLEC-10; SLG2
• Summary: SIGLECs are members of the immunoglobulin superfamily that are expressed on the cell surface. Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine-based inhibitory motifs, or ITIMs. SIGLECs are typically expressed on cells of the innate immune system, with the exception of the B-cell expressed SIGLEC6 (MIM 604405). [supplied by OMIM, Jul 2002]