Human WFDC8 activation kit by CRISPRa

CAT#: GA113987

WFDC8 CRISPRa kit - CRISPR gene activation of human WAP four-disulfide core domain 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: WFDC8
• Locus ID: 90199
• Kit Components:

  GA113987G1, WFDC8 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113987G2, WFDC8 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113987G3, WFDC8 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_130896, NM_181510
• Synonyms: C20orf170; dJ461P17.1; HEL-S-292; WAP8
• Summary: This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. The encoded protein contains a Kunitz-inhibitor domain, in addition to three WFDC domains. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the telomeric cluster. Two alternatively spliced transcript variants have been found for this gene, and they encode the same protein. [provided by RefSeq, Jul 2008]