Human KLHL13 activation kit by CRISPRa

CAT#: GA113997

KLHL13 CRISPRa kit - CRISPR gene activation of human kelch like family member 13

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KLHL13
• Locus ID: 90293
• Kit Components:

  GA113997G1, KLHL13 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113997G2, KLHL13 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113997G3, KLHL13 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001168299, NM_001168300, NM_001168301, NM_001168302, NM_001168303, NM_033495
• Synonyms: BKLHD2
• Summary: This gene encodes a BTB and kelch domain containing protein and belongs to the kelch repeat domain containing superfamily of proteins. The encoded protein functions as an adaptor protein that complexes with Cullin 3 and other proteins to form the Cullin 3-based E3 ubiquitin-protein ligase complex. This complex is necessary for proper chromosome segregation and completion of cytokinesis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]