Human DPP9 activation kit by CRISPRa

CAT#: GA114081

DPP9 CRISPRa kit - CRISPR gene activation of human dipeptidyl peptidase 9

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DPP9
• Locus ID: 91039
• Kit Components:

  GA114081G1, DPP9 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114081G2, DPP9 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114081G3, DPP9 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_139159, NM_001365987, NR_158699
• Synonyms: DP9; DPLP9; DPRP-2; DPRP2
• Summary: This gene encodes a protein that is a member of the S9B family in clan SC of the serine proteases. The protein has been shown to have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Although the activity of this protein is similar to that of dipeptidyl peptidase 4 (DPP4), it does not appear to be membrane bound. In general, dipeptidyl peptidases appear to be involved in the regulation of the activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. Several transcript variants of this gene have been described but not fully characterized. [provided by RefSeq, Jul 2008]