Human SCARF2 activation kit by CRISPRa

CAT#: GA114093

SCARF2 CRISPRa kit - CRISPR gene activation of human scavenger receptor class F member 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SCARF2
• Locus ID: 91179
• Kit Components:

  GA114093G1, SCARF2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114093G2, SCARF2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114093G3, SCARF2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_153334, NM_182895
• Synonyms: NSR1; SREC-II; SREC2; SRECRP-1; VDEGS
• Summary: The protein encoded by this gene is similar to SCARF1/SREC-I, a scavenger receptor protein that mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). This protein has only little activity of internalizing modified low density lipoproteins (LDL), but it can interact with SCARF1 through its extracellular domain. The association of this protein with SCARF1 is suppressed by the presence of scavenger ligands. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]