Human MARS2 activation kit by CRISPRa

CAT#: GA114251

MARS2 CRISPRa kit - CRISPR gene activation of human methionyl-tRNA synthetase 2, mitochondrial

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MARS2
• Locus ID: 92935
• Kit Components:

  GA114251G1, MARS2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114251G2, MARS2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114251G3, MARS2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_138395
• Synonyms: COXPD25; MetRS; mtMetRS
• Summary: This gene produces a mitochondrial methionyl-tRNA synthetase protein that is encoded by the nuclear genome and imported to the mitochondrion. This protein likely functions as a monomer and is predicted to localize to the mitochondrial matrix. Mutations in this gene are associated with the autosomal recessive neurodegenerative disease spastic ataxia-3 (SPAX3). [provided by RefSeq, Apr 2014]