Human PIGM activation kit by CRISPRa

CAT#: GA114270

PIGM CRISPRa kit - CRISPR gene activation of human phosphatidylinositol glycan anchor biosynthesis class M

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PIGM
• Locus ID: 93183
• Kit Components:

  GA114270G1, PIGM gRNA vector 1 in pCas-Guide-CRISPRa

  GA114270G2, PIGM gRNA vector 2 in pCas-Guide-CRISPRa

  GA114270G3, PIGM gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_145167
• Synonyms: GPI-MT-I
• Summary: This gene encodes a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI)-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes a mannosyltransferase, GPI-MT-I, that transfers the first mannose to GPI on the lumenal side of the endoplasmic reticulum. [provided by RefSeq, Jul 2008]