Human ACTR8 activation kit by CRISPRa

CAT#: GA114305

ACTR8 CRISPRa kit - CRISPR gene activation of human actin related protein 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ACTR8
• Locus ID: 93973
• Kit Components:

  GA114305G1, ACTR8 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114305G2, ACTR8 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114305G3, ACTR8 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_022899
• Synonyms: ARP8; hArp8; INO80N
• Summary: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA reoplication and probably DNA repair. Required for the recruitment of INO80 (and probably the INO80 complex) to sites of DNA damage. Strongly prefer nucleosomes and H3-H4 tetramers over H2A-H2B dimers, suggesting it may act as a nucleosome recognition module within the complex. [UniProtKB/Swiss-Prot Function]