Human ABCC12 activation kit by CRISPRa

CAT#: GA114337

ABCC12 CRISPRa kit - CRISPR gene activation of human ATP binding cassette subfamily C member 12

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ABCC12
• Locus ID: 94160
• Kit Components:

  GA114337G1, ABCC12 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114337G2, ABCC12 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114337G3, ABCC12 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_033226, NM_145187, NM_145188, NM_145189, NM_145190
• Synonyms: MRP9
• Summary: This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. [provided by RefSeq, Jul 2008]