Human MYL12B activation kit by CRISPRa
CAT#: GA114349
MYL12B CRISPRa kit - CRISPR gene activation of human myosin light chain 12B
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | MYL12B |
Locus ID | 103910 |
Kit Components | GA114349G1, MYL12B gRNA vector 1 in pCas-Guide-CRISPRa GA114349G2, MYL12B gRNA vector 2 in pCas-Guide-CRISPRa GA114349G3, MYL12B gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001144944, NM_001144945, NM_001144946, NM_033546 |
Synonyms | MLC-B; MRLC2 |
Summary | The activity of nonmuscle myosin II (see MYH9; MIM 160775) is regulated by phosphorylation of a regulatory light chain, such as MRLC2. This phosphorylation results in higher MgATPase activity and the assembly of myosin II filaments (Iwasaki et al., 2001 [PubMed 11942626]). [supplied by OMIM, Mar 2008] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN401372 | MYL12B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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