Human MYL12B activation kit by CRISPRa

CAT#: GA114349

MYL12B CRISPRa kit - CRISPR gene activation of human myosin light chain 12B


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol MYL12B
Locus ID 103910
Kit Components

GA114349G1, MYL12B gRNA vector 1 in pCas-Guide-CRISPRa

GA114349G2, MYL12B gRNA vector 2 in pCas-Guide-CRISPRa

GA114349G3, MYL12B gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001144944, NM_001144945, NM_001144946, NM_033546
Synonyms MLC-B; MRLC2
Summary The activity of nonmuscle myosin II (see MYH9; MIM 160775) is regulated by phosphorylation of a regulatory light chain, such as MRLC2. This phosphorylation results in higher MgATPase activity and the assembly of myosin II filaments (Iwasaki et al., 2001 [PubMed 11942626]). [supplied by OMIM, Mar 2008]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.