Human IFT43 activation kit by CRISPRa

CAT#: GA114366

IFT43 CRISPRa kit - CRISPR gene activation of human intraflagellar transport 43

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IFT43
• Locus ID: 112752
• Kit Components:

  GA114366G1, IFT43 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114366G2, IFT43 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114366G3, IFT43 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001102564, NM_001255995, NM_052873, NR_045664, NR_045665
• Synonyms: C14orf179; CED3
• Summary: This gene encodes a subunit of the intraflagellar transport complex A (IFT-A). IFT-A is a multiprotein complex that plays an important role in cilia assembly and maintenance by mediating retrograde ciliary transport. Mutations in this gene are a cause of cranioectodermal dysplasia-3 (CED3), also known as Sensenbrenner syndrome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]