Human MED8 activation kit by CRISPRa

CAT#: GA114381

MED8 CRISPRa kit - CRISPR gene activation of human mediator complex subunit 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MED8
• Locus ID: 112950
• Kit Components:

  GA114381G1, MED8 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114381G2, MED8 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114381G3, MED8 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001001651, NM_001001653, NM_001001654, NM_052877, NM_201542
• Synonyms: ARC32; MGC17544; MGC19641
• Summary: This gene encodes a protein component of the mediator complex, which aids in transcriptional activation through interaction with RNA polymerase II and gene-specific transcription factors. The encoded protein may also function in ubiquitin ligation and protein degradation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013]