Human OSBPL9 activation kit by CRISPRa

CAT#: GA114483

OSBPL9 CRISPRa kit - CRISPR gene activation of human oxysterol binding protein like 9

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: OSBPL9
• Locus ID: 114883
• Kit Components:

  GA114483G1, OSBPL9 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114483G2, OSBPL9 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114483G3, OSBPL9 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001330580, NM_024586, NM_148904, NM_148905, NM_148906, NM_148907, NM_148908, NM_148909, NR_036662, NM_001350208, NM_001350209, NM_001350210
• Synonyms: ORP-9; ORP9
• Summary: This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This family member functions as a cholesterol transfer protein that regulates Golgi structure and function. Multiple transcript variants, most of which encode distinct isoforms, have been identified. Related pseudogenes have been identified on chromosomes 3, 11 and 12. [provided by RefSeq, Jul 2010]