Human FCRL1 activation kit by CRISPRa

CAT#: GA114521

FCRL1 CRISPRa kit - CRISPR gene activation of human Fc receptor like 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FCRL1
• Locus ID: 115350
• Kit Components:

  GA114521G1, FCRL1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114521G2, FCRL1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114521G3, FCRL1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001159397, NM_001159398, NM_052938
• Synonyms: CD307a; FCRH1; IFGP1; IRTA5
• Summary: This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains three extracellular C2-like immunoglobulin domains, a transmembrane domain and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs. This protein may play a role in the regulation of cancer cell growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]