Human IL22 RA2 (IL22RA2) activation kit by CRISPRa

CAT#: GA114589

IL22RA2 CRISPRa kit - CRISPR gene activation of human interleukin 22 receptor subunit alpha 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IL22RA2
• Locus ID: 116379
• Kit Components:

  GA114589G1, IL22RA2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114589G2, IL22RA2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114589G3, IL22RA2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_052962, NM_181309, NM_181310
• Synonyms: CRF2-10; CRF2-S1; CRF2X; IL-22BP; IL-22R-alpha-2; IL-22RA2; ZCYTOR16
• Summary: This gene encodes a member of the class II cytokine receptor family. The encoded soluble protein specifically binds to and inhibits interleukin 22 activity by blocking the interaction of interleukin 22 with its cell surface receptor. The encoded protein may be important in the regulation of inflammatory response, and has been implicated in the regulation of tumorigenesis in the colon. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2013]