Human ADSSL1 activation kit by CRISPRa

CAT#: GA114777

ADSSL1 CRISPRa kit - CRISPR gene activation of human adenylosuccinate synthase like 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ADSSL1
• Locus ID: 122622
• Kit Components:

  GA114777G1, ADSSL1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114777G2, ADSSL1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114777G3, ADSSL1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001320424, NM_152328, NM_199165
• Synonyms: MPD5
• Summary: This gene encodes a member of the adenylosuccinate synthase family of proteins. The encoded muscle-specific enzyme plays a role in the purine nucleotide cycle by catalyzing the first step in the conversion of inosine monophosphate (IMP) to adenosine monophosphate (AMP). Mutations in this gene may cause adolescent onset distal myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]