Human METTL23 activation kit by CRISPRa

CAT#: GA114844

METTL23 CRISPRa kit - CRISPR gene activation of human methyltransferase like 23

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: METTL23
• Locus ID: 124512
• Kit Components:

  GA114844G1, METTL23 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114844G2, METTL23 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114844G3, METTL23 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001080510, NM_001206983, NM_001206984, NM_001206985, NM_001206986, NM_001206987, NM_001302703, NM_001302704, NM_001302705, NR_038193
• Synonyms: C17orf95; MRT44
• Summary: The protein encoded by this gene functions as a transcription factor regulator in the transcriptional pathway for human cognition. It is a partner of the alpha subunit of the GA-binding protein transcription factor. Mutations in this gene cause mild autosomal recessive intellectual disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]