Human GNPDA2 activation kit by CRISPRa

CAT#: GA115183

GNPDA2 CRISPRa kit - CRISPR gene activation of human glucosamine-6-phosphate deaminase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GNPDA2
• Locus ID: 132789
• Kit Components:

  GA115183G1, GNPDA2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA115183G2, GNPDA2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA115183G3, GNPDA2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001270880, NM_001270881, NM_138335, NR_073094, NR_073095
• Synonyms: GNP2; SB52
• Summary: The protein encoded by this gene is an allosteric enzyme that catalyzes the reversible reaction converting D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium. Variations of this gene have been reported to be associated with influencing body mass index and susceptibility to obesity. A pseudogene of this gene is located on chromosome 9. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]