Human HGSNAT activation kit by CRISPRa

CAT#: GA115298

HGSNAT CRISPRa kit - CRISPR gene activation of human heparan-alpha-glucosaminide N-acetyltransferase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HGSNAT
• Locus ID: 138050
• Kit Components:

  GA115298G1, HGSNAT gRNA vector 1 in pCas-Guide-CRISPRa

  GA115298G2, HGSNAT gRNA vector 2 in pCas-Guide-CRISPRa

  GA115298G3, HGSNAT gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_152419, NM_001363228, NM_001363229, NM_001363227
• Synonyms: HGNAT; MPS3C; TMEM76
• Summary: This gene encodes a lysosomal acetyltransferase, which is one of several enzymes involved in the lysosomal degradation of heparin sulfate. Mutations in this gene are associated with Sanfilippo syndrome C, one type of the lysosomal storage disease mucopolysaccaridosis III, which results from impaired degradation of heparan sulfate. [provided by RefSeq, Jan 2009]