Human UPRT activation kit by CRISPRa

CAT#: GA115344

UPRT CRISPRa kit - CRISPR gene activation of human uracil phosphoribosyltransferase homolog

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: UPRT
• Locus ID: 139596
• Kit Components:

  GA115344G1, UPRT gRNA vector 1 in pCas-Guide-CRISPRa

  GA115344G2, UPRT gRNA vector 2 in pCas-Guide-CRISPRa

  GA115344G3, UPRT gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001307944, NM_145052, NR_030774, NM_001363821
• Synonyms: FUR1; UPP
• Summary: This gene encodes uracil phosphoribosyltransferase, which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. The enzyme localizes to the nucleus and cytoplasm. The protein is a potential target for rational design of drugs to treat parasitic infections and cancer. [provided by RefSeq, Nov 2009]