Human ASB6 activation kit by CRISPRa

CAT#: GA115364

ASB6 CRISPRa kit - CRISPR gene activation of human ankyrin repeat and SOCS box containing 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ASB6
• Locus ID: 140459
• Kit Components:

  GA115364G1, ASB6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA115364G2, ASB6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA115364G3, ASB6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001202403, NM_017873, NM_177999
• Synonyms: FLJ20548; MGC1024
• Summary: The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contain a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box, similar to the F-box, acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jan 2011]