Human Prickle (PRICKLE1) activation kit by CRISPRa
CAT#: GA115484
PRICKLE1 CRISPRa kit - CRISPR gene activation of human prickle planar cell polarity protein 1
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | PRICKLE1 |
Locus ID | 144165 |
Kit Components | GA115484G1, PRICKLE1 gRNA vector 1 in pCas-Guide-CRISPRa GA115484G2, PRICKLE1 gRNA vector 2 in pCas-Guide-CRISPRa GA115484G3, PRICKLE1 gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001144881, NM_001144882, NM_001144883, NM_153026 |
Synonyms | EPM1B; RILP |
Summary | This gene encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway. The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/NRSF and REST4. Mutations in this gene have been linked to progressive myoclonus epilepsy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq, Sep 2009] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN423861 | PRICKLE1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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