Human IL23 Receptor (IL23R) activation kit by CRISPRa
CAT#: GA115701
IL23R CRISPRa kit - CRISPR gene activation of human interleukin 23 receptor
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | IL23R |
Locus ID | 149233 |
Kit Components | GA115701G1, IL23R gRNA vector 1 in pCas-Guide-CRISPRa GA115701G2, IL23R gRNA vector 2 in pCas-Guide-CRISPRa GA115701G3, IL23R gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_144701 |
Synonyms | interleukin 23 receptor; OTTHUMP00000010660 |
Summary | The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner. [provided by RefSeq, Jul 2008] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN411477 | IL23R - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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