Human IL23 Receptor (IL23R) activation kit by CRISPRa

CAT#: GA115701

IL23R CRISPRa kit - CRISPR gene activation of human interleukin 23 receptor


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol IL23R
Locus ID 149233
Kit Components

GA115701G1, IL23R gRNA vector 1 in pCas-Guide-CRISPRa

GA115701G2, IL23R gRNA vector 2 in pCas-Guide-CRISPRa

GA115701G3, IL23R gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_144701
Synonyms interleukin 23 receptor; OTTHUMP00000010660
Summary The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner. [provided by RefSeq, Jul 2008]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.